The Ministry of Health and Child Care has launched a transformative single-dose regimen of the Human Papillomavirus (HPV) vaccine this week, a strategic shift aimed at drastically reducing the country’s high burden of cervical cancer.

The new one-shot vaccine, which provides lifetime protection against the primary cause of cervical cancer, the nation’s leading cancer killer of women, was rolled out in Matabeleland South Province.

This move replaces the previous two-dose schedule.

Minister of Health and Child Care, Dr. Douglas Mombeshora, confirmed the change, citing improved protection and logistical advantages over the former two-dose plan.

“Research has since shown that with slight modification, one dose provides sufficient protection,” Dr. Mombeshora stated.

The critical factor driving the switch is addressing high dropout rates, which previously led to incomplete vaccination.

“We had issues of compliance—some would get one dose and never return for the second, meaning they were lost before completing the schedule. Anyone who receives one dose is now protected. There is no need to worry about follow-up,” he explained.

Beyond improved compliance, the single-dose strategy offers a major national cost benefit, with the country now paying for one dose instead of two at the same unit price.

The vaccine is integrated into routine national immunisation programmes and is now accessible at all routine vaccination points, moving beyond the previous school-visit system.

It targets girls aged 10 and above, prior to sexual activity, to prevent infection.

The Minister also highlighted the specific importance for women living with HIV. “Women with HIV are six times more likely to develop cervical cancer, so protecting our girls today safeguards tomorrow’s mothers, leaders and innovators,” he said.

UNICEF Representative, Etona Ekole, hailed the launch as a milestone.

“The likelihood of drop-outs is now significantly reduced. It’s a major breakthrough.

“It will make a huge difference to the lives of young girls in Zimbabwe,” she said, confirming UNICEF has mobilised resources to support the government’s initiative.